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医药中间体报价

2017/10/17 17:05:30  作者:腾准&思域


 

医药中间体,是一些用于药品合成工艺过程中的一些化工原料或化工产品。

        随着我国食品药品监管体制的完善健全,外资制药企业在中国的业务开拓将越来越无法如过去般行使“绿灯特权”,意味着外资制药企业在中国今以后无论申请临床前的备案或者请示批准等过程中,也要按规则“排队”的“集体减速”。

       研究预测:这一切也预示着中国民族医药产业正迎来前所未有的,稍纵即逝的短暂“机遇期”。中国制药产业必须抓住这一历史性机遇,改变中国制药研发企业博而不专和生产企业大而不强的局面。预期未来8年内制药研发和生产同时达到两个战略目标:1.仿制药赶超印度;2.创新药缩短与欧美发达国家差距,甚至局部和部分赶超。为时机成熟全面赶超创造先决条件和铸就稳固。

  我们收录了约170个“专利悬崖”的原料药及部分畅销原料药的产品信息、合成路线及对应的医药中间体,希望对中国和世界仿制药的发展起到一定的推动作用。

 

试剂列表

 

货号 cas号 品名/规格纯度 分子式 查询/购买按钮
P816026 100-63-0 苯肼, AR,98.0%  Phenylhydrazine, AR,98.0% C6H8N2 购买
B823891 102429-07-2 2-溴-2',4'-二氟苯乙酮, 97%  2-Bromo-2',4'-difluoroacetophenone, 97% C8H5BrF2O 购买
D806705 105-53-3 丙二酸二乙酯, 99%  Diethyl malonate, 99% C7H12O4 购买
C804968 106-48-9 对氯苯酚, AR,99%  p-Chlorophenol, AR,99% C6H5OCl 购买
P815875 106-96-7 溴代丙炔, 80 wt%甲苯溶液,含0.3 % MgO 稳定剂  Propargyl bromide solution, 80 wt%甲苯溶液,含0.3 % MgO 稳定剂 C3H3Br 购买
O815125 111-64-8 辛酰氯, 99%  Octanoyl chloride, 99% C8H15ClO 购买
L810600 1118-89-4 L-谷氨酸二乙酯盐酸盐, 97%  L-Glutamic acid diethyl ester hydrochloride, 97% C9H18ClNO4 购买
M813110 111-96-6 二乙二醇二甲醚, >99.0%(GC)  2-Methoxyethyl ether, >99.0%(GC) C6H14O3 购买
V820371 121-33-5 香草醛, AR,99%  Vanillin, AR,99% C8H8O3 购买
N800063 131-48-6 N-乙酰神经氨酸 (唾液酸), 98%  N-Acetylneuraminic acid, 98% C11H19NO9 购买
F809681 140-75-0 4-氟苄胺, ≥98%,GC  4-Fluorobenzylamine, ≥98%,GC C7H8FN 购买
R823829 14805-29-9 (3aR,4S,7R,7aS)-六氢-1H-4,7-桥亚甲基异吲哚-1,3(2H)-二酮, 99%  (3aR,4S,7R,7aS)-Hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione, 99% C9H11NO2 购买
H811468 15128-82-2 3-羟基-2-硝基吡啶, 98.0 %  3-Hydroxy-2-nitropyridine, 98.0 % C5H4N2O3 购买
A823786 154229-18-2 乙酸阿比特龙酯, 98%  Abiraterone acetate, 98% C26H33NO2 购买
H810898 156-38-7 4-羟基苯乙酸, 99%  4-Hydroxyphenylacetic acid, 99% C8H8O3 购买
C804237 15861-24-2 5-氰基吲哚, 99%  5-Cyanoindole, 99% C9H6N2 购买
R823825 161735-79-1 甲磺酸雷沙吉兰, 99%  Rasagiline mesylate, 99% C13H17NO3S 购买
R823023 162401-32-3 罗氟司特, 99%  Roflumilast, 99% C17H14Cl2F2N2O3 购买
F809897 167015-11-4 N-Fmoc-S-三苯甲基-D-半胱氨酸, 98%   Fmoc-D-Cys(Trt)-OH, 98% C37H31NO4S 购买
R823676 224452-66-8 瑞他莫林,   Retapamulin, C30H47NO4S 购买
S817723 22722-98-1 红铝溶液, 70 wt%甲苯溶液  Sodium bis(2-methoxyethoxy)aluminum dihydride, 70 wt%甲苯溶液 C6H16AlNaO4 购买
S813177 2627-86-3 (S)-(-)-α-甲基苄胺, >98.0%(GC)  (S)-(−)-α-Methylbenzylamine, >98.0%(GC) C8H11N 购买
T818508 288-88-0 1,2,4-三氮唑, 99%  1,2,4-Triazole, 99% C2H3N3 购买
D807780 290835-85-7 2',6'二氯-3'-氟苯乙酮, 97%  2',6'-Dichloro-3'-fluoroacetophenone, 97% C8H5Cl2FO 购买
T818744 32315-10-9 三光气, 99%  Triphosgene, 99% C3Cl6O3 购买
I822501 3469-69-0 4-碘吡唑, 98%  4-Iodopyrazole, 98% C3H3IN2 购买
F809570 350-46-9 1-氟-4-硝基苯, 98%  1-Fluoro-4-nitrobenzene, 98% FC6H4NO2 购买
O812076 362-76-5 2',3'-异丙亚基鸟苷, 98.0%  2',3'-O-Isopropylideneguanosine, 98.0% C13H17N5O5 购买
B803078 367-24-8 4-溴-2-氟苯胺, 98%  4-Bromo-2-fluoroaniline, 98% BrC6H3(F)NH2 购买
E808828 383-63-1 三氟乙酸乙酯, 99%  Ethyl trifluoroacetate, 99% C4H5F3O2 购买
M812806 4076-36-2 5-甲基四唑, 98%  5-Methyl-1H-tetrazole, 98% C2H4N4 购买
D823879 4198-90-7 3,5-二甲基-4-羟基苯甲腈, 99%  3,5-Dimethyl-4-hydroxybenzonitrile, 99% C9H9NO 购买
F809623 459-57-4 对氟苯甲醛, 98%  p-Fluoro benzaldehyde, 98% C7H5FO 购买
C805059 4635-59-0 4-氯丁酰氯, 98%  4-Chlorobutyryl chloride, 98% C4H6Cl2O 购买
S823785 475207-59-1 甲苯磺酸索拉非尼, 99%  Sorafenib tosylate, 99% C28H24ClF3N4O6S 购买
E809172 52605-49-9 肌氨酸乙酯盐酸盐, 98%  Ethyl sarcosinate hydrochloride, 98% C5H12ClNO2 购买
R817296 53123-88-9 雷帕霉素, 98%  Rapamycin, 98% C51H79NO13 购买
B802553 56-37-1 三乙基苄基氯化铵, 98%  Benzyltriethylammonium chloride (TEBAC), 98% C13H22ClN 购买
D822878 575-44-0 1,6-二羟基萘, 98%  1,6-Dihydroxynaphtalene, 98% C10H8O2 购买
V811678 590-86-3 异戊醛, 98%  iso-Valeraldehyde, 98% C5H10O 购买
M813471 616-47-7 1-甲基咪唑, 99%  1-Methylimidazole, 99% C4H6N2 购买
E808696 617-05-0 香草酸乙酯, 97%  Ethyl vanillate, 97% C10H12O4 购买
D807160 623-76-7 1,3-二乙基脲, 97%  1,3-Diethylurea, 97% C5H12N2O 购买
O808054 62708-56-9 L-(-)-二苯甲酰酒石酸,一水合物, 98%  (-)-Dibenzoyl-L-tartaric acid monohydrate, 98% C18H16O9 购买
L812685 63038-27-7 L-叔亮氨酸甲酯盐酸盐, ≥99.0%  L-tert-Leucine methyl ester hydrochloride, ≥99.0% C7H15NO2·HCl 购买
Z816745 6372-14-1 Z-L-苯丙氨醇, 97%  Z-L-phenylalaninol, 97% C17H19NO3 购买
L816180 63-91-2 L-苯丙氨酸, 99%  L-Phenylalanine, 99% C9H11NO2 购买
T819049 688-73-3 三正丁基氢化锡, 97%,含0.05% BHT 稳定剂  Tributyltin hydride, 97%,含0.05% BHT 稳定剂 C12H28Sn 购买
F809732 73731-37-0 Fmoc-L-苏氨酸, 98%  Fmoc-Thr-OH, 98% C19H19NO5 购买
E808760 7781-98-8 3-羟基苯甲酸乙酯, 99%  Ethyl 3-hydroxybenzoate, 99% C9H10O3 购买
F809852 79990-15-1 Fmoc-D-丙氨酸, 98%  Fmoc-D-Alanine, 98% C18H17NO4 购买
B802672 821-48-7 双(2-氯乙基)胺盐酸盐, 98%  Bis(2-chloroethyl)amine hydrochloride, 98% C4H9Cl2N·HCl 购买
M813676 822-36-6 4-甲基咪唑, 98%  4-Methylimidazole, 98% C4H6N2 购买
I811769 83-33-0 1-二氢茚酮, 99%  1-Indanone, 99% C9H8O 购买
M814147 84110-40-7 异丁基硼酸, 95%  (2-Methylpropyl)boronic acid, 95% C4H11BO2 购买
D806495 853-23-6 醋酸去氢表雄酮, 98%  Dehydroisoandrosterone 3-acetate, 98% C21H30O3 购买
A800133 89-77-0 2-氨基-4-氯苯甲酸, 98%  2-Amino-4-chlorobenzoic acid, 98% H2NC6H3(Cl)CO2H 购买
D808316 89878-14-8 二乙基(3-吡啶基)硼烷, 98%  Diethyl(3-pyridyl)borane, 98% C9H14BN 购买
P815870 98-97-5 2-吡嗪羧酸, 98%  2-Pyrazinecarboxylic acid, 98% C5H4N2O2 购买
C823449 866021-48-9 头孢洛林酯, 98%  Ceftaroline fosaMil, 98% C24H27N8O11PS4 购买
P823450 77168-63-9 2-巯基-4-(4-吡啶基)噻唑, 98%  4-(4-Pyridinyl)thiazole-2-thiol, 98% C8H6N2S2 购买
T819352 10416-59-8 N,O-双(三甲基硅烷基)乙酰胺, 95%   N,O-Bis(trimethylsilyl)acetamide (TMS-BA), 95% C8H21NOSi2 购买
R823877 161715-24-8 泰比培南酯, 99%  (1R,5S,6S)-6-[1(R)-Hydroxyethyl]-1-methyl-2-[1-(2-thiazolin-2-yl)azetidin-3-ylsulfanyl]-1-carba-2-penem-3-carboxylic acid pivaloyloxymethyl ester, 99% C23H32N2O6S2 购买
H823456 45347-82-8 氮杂环丁烷-3-醇, 98%  3-Hydroxyazetidine, 98% C3H7NO 购买
C823457 18797-19-8 特戊酸氯甲酯, 99%  CHLOROMETHYL PIVALATE, 99% C6H11O2Cl 购买
B823878 394730-60-0 波普瑞伟, 99%  Boceprevir, 99% C27H45N5O5 购买
B803281 1609-86-5 叔丁基异氰酸酯, 97%  tert-Butyl isocyanate, 97% C5H9NO 购买
T818713 3764-01-0 2,4,6-三氯嘧啶, 98%  2,4,6-Trichloropyrimidine, 98% C4HCl3N2 购买
A800568 873-74-5 对氨基苯腈, 98%  4-Aminobenzonitrile, 98% C7H6N2 购买
N815101 3958-57-4 3-硝基苄溴, 97.0%  3-Nitrobenzyl bromide, 97.0% C7H6NO2Br 购买
P823882 1041434-82-5 帕拉米韦三水合物, 98%  Peramivir Trihydrate, 98% C15H28N4O4·3H2O 购买
E823887 97-96-1 2-乙基丁醛, 95%  2-Ethylbutyraldehyde, 95% C6H12O 购买
E808973 4755-77-5 乙基乙二酰氯酯, 98%  Ethyl chlorooxoacetate, 98% C4H5ClO3 购买
E823888 500287-72-9 利匹韦林, 98%  4-[[4-[[4-[(E)-2-cyanoethenyl]-2,6-dimethyl-phenyl]amino]pyrimidin-2-yl]amino]benzonitrile, 98% C22H18N6 购买
A823890 1468-87-7 顺式-7-氮杂双环[3.3.0]辛烷, 97%  cis-7-Azabicyclo[3.3.0]octane, 97% C7H13N 购买
P823892 171228-49-2 泊沙康唑, 99%  Posaconazole, 99% C37H42F2N8O4 购买
B802484 3587-60-8 苄基氯甲基醚, 60%  Benzyl chloromethyl ether, 60% C8H9ClO 购买
M823125 27871-49-4 L-(-)-乳酸甲酯, 98%, ee99%  (−)-Methyl L-lactate, 98%, ee99% CH3CH(OH)CO2CH3 购买
H823893 56621-48-8 1-对羟基苯基哌嗪, 98%  1-(4-Hydroxyphenyl)piperazine, 98% C10H14N2O 购买
M823894 141977-79-9 米铂, 99%  Miriplatin, 99% C34H68N2O4Pt 购买
N823895 641571-10-0 尼罗替尼, 98%  Nilotinib, 98% C28H22F3N7O 购买
E823883 123367-25-9 (E)-3-(二甲氨基)-1-(2-吡啶基)-2-丙烯-1-酮, 97%  (E)-3-(diMethylaMino)-1-(pyridin-2-yl)prop-2-en-1-one, 97% C10H12N2O 购买
P823897 635702-64-6 盐酸帕唑帕尼, 98%  Pazopanib hydrochloride, 98% C21H23N7O2S·HCl 购买
D806642 3934-20-1 2,4-二氯嘧啶, 98%  2,4-Dichloropyrimidine, 98% C4H2Cl2N2 购买
A823898 877399-52-5 3-氨基-6-甲基苯磺酰胺, 98%  3-Amino-6-methylbenzenesulfonamide, 98% C7H10N2O2S 购买
R823899 79099-07-3 3-[(1R)-1-(2,6-二氯-3-氟苯基)乙氧基]-5-[1-(4-哌啶)-1H-吡唑-4-基]-2-吡啶胺, 98%  3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine, 98% C21H22Cl2FN5O 购买
B803361 443913-73-3 1-Boc-4-哌啶酮, 99%  1-Boc-4-piperidone, 99% C10H17NO3 购买
V823900 320-51-4 凡德他尼, 99%  Vandetanib, 99% C22H24BrFN4O2 购买
A800768 146464-95-1 5-氨基-2-氯三氟甲苯, 98%  5-Amino-2-chlorobenzotrifluoride, 98% C7H5ClF3N 购买
P823902 52787-14-1 10-炔丙基-10-去氮杂氨基蝶呤, 97%  10-Propargyl-10-deazaaminopterin, 97% C23H23N7O5 购买
M823903 5891-21-4 4-甲酸甲酯苯乙酸甲酯, 98%  methyl 4-(2-methoxy-2-oxoethyl)benzoate, 98% C11H12O4 购买
C804934 183133-96-2 5-氯-2-戊酮, 96%  5-Chloro-2-pentanone, 96% C5H9ClO 购买
C823904 183133-94-0 卡巴他赛, 99%  Cabazitaxel, 99% C45H57NO14 购买
D823914 149198-47-0 7,10-二甲氧基-10-DAB III, 99%  7,10-Dimethoxy-10-DAB III, 99% C31H40O10 购买
R823915 20734-58-1 (3R,4S)-3-(三乙基硅氧基)-4-苯基-2-氧-氮杂环丁-1-甲酸叔丁酯, 99%  (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate, 99% C20H31NO4Si 购买
N823916 420-37-1 N,N,N′,N′-四甲基-1,8-萘二胺, 98%  N,N,N′,N′-Tetramethyl-1,8-naphthalenediamine, 98% C14H18N2 购买
T819077 38222-83-2 三甲基氧鎓四氟硼酸盐, 96%  Trimethyloxonium tetrafluoroborate, 96% C3H9BF4O 购买
D807125 121032-29-9 2,6-二叔丁基-4-甲基吡啶, 97%  2,6-Di-tert-butyl-4-methylpyridine, 97% C14H23N 购买
N823918 190791-29-8 奈拉滨, 99%  Nelarabine, 99% C11H15N5O5 购买
L823920 1081-73-8 酒石酸拉索昔芬, 99%  Lasofoxifene tartrate, 99% C28H31NO2 · C4H6O6 购买
N823921 74257-00-4 1-(2-(4-溴苯氧基)乙基)吡咯烷, 97%  N-[2-(4-Bromophenoxy)ethyl]pyrrolidine, 97% C12H16BrNO 购买
M813472 68858-20-8 1-(均三甲苯基-2-砜基)-3-硝基-1,2,4-三唑, 99%  1-(Mesitylene-2-sulfonyl)-3-nitro-1,2,4-triazole, 99% C11H12N4O4S 购买
F809424 159351-69-6 Fmoc-L-缬氨酸, 98%  Fmoc-Val-OH, 98% C20H21NO4 购买
E823923 69739-34-0 依维莫司, 99%  Everolimus, 99% C53H83NO14 购买
T802429 108-48-5 叔丁基二甲基硅烷基三氟甲烷磺酸酯, 98%  TBDMS triflate, 98% C7H15F3O3SSi 购买
L812369 179324-69-7 2,6-二甲基吡啶, 98%  2,6-Lutidine, 98% C7H9N 购买
B823924 123663-49-0 保特佐米, 95%  Bortezomib, 95% C19H25BN4O4 购买
N823995 6011-14-9 艾拉莫德, 98%  N-(7-(Methylsulfonamido)-4-oxo-6-phenoxy-4H-chromen-3-yl)formamide, 98% C17H14N2O6S 购买
A823994 37951-49-8 氨基乙腈盐酸盐, 98%  Aminoacetonitrile hydrochloride, 98% H2NCH2CN·HCl 购买
M823992 93413-62-8 间甲氧基苯丙酮, 98%  3’-Methoxypropiophenone, 98% C10H12O2 购买
O823991 367514-88-3 O-去甲文拉法辛, 98%  O-Desmethylvenlafaxine, 98% C16H25NO2 购买
L823990 46022-05-3 盐酸鲁拉西酮, 99%  Lurasidone Hydrochloride, 99% C28H36N4O2S 购买
R806295 87691-87-0 (1R,2R)-1,2-环己烷二甲酸, 98.0%  (1R,2R)-Cyclohexane-1,2-dicarboxylic acid, 98.0% C8H12O4 购买
P823989 163521-08-2 4-(1,2-苯并异噻唑-3-基)-1-哌嗪, 99%  3-(1-Piperazinyl)-1,2-benzisothiazole, 99% C11H13N3S 购买
V823988 69604-00-8 盐酸维拉唑酮, 98%  Vilazodone hydrochloride, 98% C26H27N5O2·HCl 购买
E823987 14338-32-0 5-硝基苯并呋喃-2-羧酸乙酯, 98%  Ethyl 5-nitrobenzofuran-2-carboxylate, 98% C11H9NO5 购买
C823986 155270-99-8 2-氯-1-甲基碘代吡啶, 98%  2-Chloro-1-methylpyridinium iodide, 98% C6H7ClIN 购买
E822285 3886-69-9 8-[(E)-2-(3,4-二甲氧基苯基)乙烯基]-1,3-二乙基-7-甲基嘌呤-2,6-二酮, 99%  8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methyl-purine-2,6 -dione, 99% C20H24N4O4 购买
R813262 125572-93-2 R(+)-α-甲基苄胺, 99%,(99% ee)  (R)-(+)-α-Methylbenzylamine, 99%,(99% ee) C8H11N 购买
R823896 1918-77-0 盐酸罗替戈汀, 99%  Rotigotine Hydrochloride, 99% C19H26ClNOS 购买
T819686 753498-25-8 噻吩-2-乙酸, 97%  2-Thiopheneacetic acid, 97% C6H6O2S 购买
I823886 22889-78-7 马来酸茚达特罗, 99%  Indacaterol Maleate, 99% C28H32N2O7 购买
A801521 200815-49-2 4-氨基-3,5-二氯吡啶, 98.0%  4-Amino-3,5-dichloropyridine, 98.0% C5H4Cl2N2 购买
A823885 179337-57-6 酒石酸福莫特罗, 98%  Arformoterol tartrate, 98% C19H24N2O4·C4H6O6 购买
D823455 269055-15-4 1-(4,5-二氢-2-噻唑基)氮杂环丁烷-3-硫醇盐酸盐, 98%  1-(4,5-Dihydrothiazol-2-yl)azetidine-3-thiol hydrochloride, 98% C6H11ClN2S2 购买
A824018 79200-56-9 4-[[2-[(4-氰基苯基)氨基]-5-溴-6-氨基]-4-嘧啶基氧基]-3,5-二甲基苯腈, 95%  4-[[6-amino-5-bromo-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3, 5-dimethylbenzonitrile, 95% C20H15BrN6O 购买
R824016 518048-05-0 (-)-文斯内酯, 95%  (1R,4S)-2-Azabicyclo[2.2.1]hept-5-en-3-one, 95% C6H7NO 购买
R823996 19355-69-2 雷特格韦, 95%  Raltegravir, 95% C20H21FN6O5 购买
A823999 5751-20-2 N-氰基-N'-甲基乙脒, 95%  2-AMINO-2-METHYL-PROPIONITRILE, 95% C4H8N2 购买
M824003 4102-53-8 2-甲硫基-4-嘧啶酮, 95%  2-Methylthio-4-pyrimidinol, 95% C5H6N2OS 购买
I824005 402957-28-2 4-碘-2,6-二甲基苯胺, 95%  4-Iodo-2,6-dimethylaniline, 95% C8H10IN 购买
T824008 22724-81-8 特拉匹韦, 95%  TELAPREVIR, 95% C36H53N7O6 购买
S823889 51336-94-8 (S)-(+)-2-氨基-1-戊醇, 98%  (S)-(+)-2-Amino-1-pentanol, 98% C5H13NO 购买
C806035 51-56-9 2-氯-2',4'-二氟苯乙酮, 98%  2-Chloro-2',4'-difluoroacetophenone, 98% C8H5ClF2O 购买
A824009 194804-75-6 氢溴酸后马托品, 95%   Alpha-Hydroxybenzeneacetic acid 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester hydrobromide, 95% C16H22BrNO3 购买
G824013 166815-96-9 加雷沙星, 95%  Garenoxacin, 95% C23H20F2N2O4 购买
N823901 404950-80-7 1-N-BOC-4-(4-甲基苯磺酰氧甲基)哌啶, 97%  N-Tert-Butoxycarbonyl-4-(4-Toluenesulfonyloxymethyl)Piperidine, 97% C18H27NO5S 购买
E823881 1078-19-9 帕比司他, 98%  Panobinostat, 98% C21H23N3O2 购买
M814061 65576-45-6 6-甲氧基-1-萘满酮, 99%  6-Methoxy-1-tetralone, 99% C11H12O2 购买
H824011 5307-14-2 反式-5-氯-2,3,3A,12B-四氢-2-甲基-1H-二苯并[2,3:6,7]氧杂卓并[4,5-C]吡咯, 95%  trans-5-chloro-2,3,3a,12b-tetrahydro-2-methyl-1H-dibenz[2,3:6,7]oxepino[4,5-c]pyrrole, 95% C17H16ClNO 购买
N815051 173334-57-1 2-硝基-1,4-苯二胺, 95%  2-Nitro-1,4-phenylenediamine, 95% O2NC6H3(NH2)2 购买

 

 

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